Protein adsorption and functional hybrid carriers

Magdalena Goncerz

Magdalena Szota, MSc Eng.

+48 12 6395 203

Position

PhD student

Magdalena Goncerz graduated from the Krakow University of Technology in the field of biotechnology. In her master’s thesis, she worked on Controlled Drug Delivery Systems (CDDS). Currently, she is preparing a doctoral dissertation in this field of nanotechnology. Its main research areas are the physicochemistry of colloidal systems, in particular the physicochemical characteristics of dendrimers and proteins in the context of their interactions with anticancer drugs.

Education

2019 – current – PhD Studies (Chemistry) – Krakow School of Interdisciplinary PhD Studies  at Jerzy Haber Institute of  Catalysis and Surface Chemistry, PAS

 

2018 – 2019 – Master of Science in Biotechnology (Industrial and Environmental Biotechnology), the Department of Chemical Engineering and Technology at Cracow University of Technology

 

2014 – 2018 – Engineer’s Degree in Biotechnology (Industrial and Environmental Biotechnology), the Department of Chemical Engineering and Technology at Cracow University of Technology

Experience

March 2022 – May 2024

Participation in OPUS 21, ST-5, 2021/41/B/ST5/02233 program Structure and Function of the Protein Corona on the Surface of Nanoparticles funded by the National Science Centre in Poland at Jerzy Haber Institute of Catalysis and Surface Chemistry, PAS

February 2023 – March 2023 

Research Internship 

Department of Physics, University of Glasgow, Scotland, UK.

November 2021 – December 2021 

Research Internship 

Department of Chemical and Geological Sciences, University of Cagliari, Italy.

September 2021 – October 2021 

Research Internship 

Department of Chemical and Geological Sciences, University of Cagliari, Italy.

November 2019 – June 2021 

Participation in OPUS 12, ST-5, 2016/23/B/ST5/02788 program Dendrimers as a platform for the design of biologically active carriers funded by the National Science Centre in Poland at Jerzy Haber Institute of Catalysis and Surface Chemistry, PAS

Publications

Szota M., Szwedowicz U., Rembiałowska N., Janicka-Klos A., Doveiko D., Chen Y., Kulbacka J., Jachimska B.* “Dendrimer Platforms for Targeted Doxorubicin Delivery—Physicochemical Properties in Context of Biological Responses” International Journal of Molecular Sciences 2024, 25(13), 7201

 

Adamczyk O., Szota M., Rakowski K., Prochownik M., Doveiko D., Chen Y., Jachimska B.* “Bovine Serum Albumin as a Platform for Designing Biologically Active Nanocarriers—Experimental and Computational Studies” International Journal of Molecular Sciences 2024, 25, 37

 

Tworek P., Rakowski K., Szota M., Lekka M., Jachimska B.*, “Changes in Secondary Structure and Properties of Bovine Serum Albumin as a Result of Interactions with Gold Surface” ChemPhysChem2024, 25(2):e202300505.

 

Szota M. and Jachimska B.*, “Effect of Alkaline Conditions on Forming an Effective G4.0 PAMAM Complex with Doxorubicin” Pharmaceutics, 2023, 15(3), 875

 

Szota M., Wolski P., Carucci C., Cesare F. M., Gurgul J., Panczyk T., Salis A., Jachimska B.*, “Effect of Ionization Degree of Poly(amidoamine) Dendrimer and 5-Fluorouracil on the Efficiency of Complex Formation—A Theoretical and Experimental Approach” International Journal of Molecular Sciences2023, 24, 819

 

A. Sobiepanek, P. D. Kowalska, M. Szota,  T. Grzywa, J. Nowak, P. K. Włodarski, R. Galus, B. Jachimska, T. Kobiela, “Novel diagnostic and prognostic factors for the advanced melanoma based on the glycosylation-related changes studied by biophysical profiling methods,” Biosens. Bioelectron., vol. 203, no. October 2021, p. 114046, 2022, doi: 10.1016/j.bios.2022.114046.

 

Szota, M.; Reczyńska-Kolman, K.; Pamuła, E.; Michel, O.; Kulbacka, J.; Jachimska, B. Poly(amidoamine) Dendrimers as Nanocarriers for 5-Fluorouracil: Effectiveness of Complex Formation and Cytotoxicity Studies. Int. J. Mol. Sci. 202122, 11167. https://doi.org/10.3390/ijms222011167

Membership in professional associations

  • PhD Student Council at Jerzy Haber Institute of Catalysis and Surface Chemistry PAS – PhD Student Body Member

 

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